PRP & BMAC for Joint Preservation

Platelet-Rich Plasma (PRP) and Bone Marrow Aspirate Concentrate (BMAC) are biologic therapies used as part of a joint preservation strategy to support the body's natural healing processes. These treatments utilise concentrated biological components derived from the patient's own blood or bone marrow, respectively, and are used to potentially reduce inflammation, support tissue repair, and help delay or avoid the need for joint replacement surgery in selected patients.

What Is PRP?

Platelet-Rich Plasma is prepared by drawing a small sample of the patient's own blood, which is then processed by centrifugation to concentrate the platelets and their associated growth factors. The resulting PRP preparation is injected into the affected joint or tissue.

Platelets carry a variety of growth factors that play a role in tissue repair and the modulation of the local biological environment. PRP is used as an adjunct in the management of joint pain and certain soft tissue conditions.

What Is BMAC?

Bone Marrow Aspirate Concentrate is obtained by aspirating bone marrow — usually from the iliac crest (pelvis) — and concentrating it to yield a preparation rich in mesenchymal stem cells, growth factors, and other biologically active components. BMAC is used for more advanced joint preservation scenarios where a more potent biologic stimulus may be beneficial.

Applications in Joint Preservation

PRP and BMAC may be considered as part of the management of:

• Early to moderate knee osteoarthritis
• Cartilage defects and chondral injuries
• Tendon and ligament conditions
• Post-operative support to enhance healing
• Joint pain management in patients seeking to delay surgical intervention

These therapies are typically considered when non-surgical measures such as physiotherapy, lifestyle modification, and conventional injections have not provided adequate relief, but where the patient is not yet a candidate or ready for joint replacement surgery.

The Treatment Process

PRP
Blood is drawn from the patient in the clinic or procedure room. The sample is centrifuged to separate and concentrate the platelets. The PRP is then injected into the target joint or tissue under appropriate guidance.

BMAC
Bone marrow is aspirated under local anaesthesia, usually from the posterior iliac crest. The aspirate is processed to concentrate the cellular components and injected into the target area, often under imaging guidance or during an arthroscopic procedure.

Considerations

PRP and BMAC are autologous treatments — meaning they use the patient's own biological material — which reduces the risk of allergic reaction or disease transmission. The evidence for these therapies continues to evolve, and outcomes vary between individuals depending on the underlying condition, disease severity, and patient factors.

A thorough clinical assessment, including imaging and review of previous treatments, is carried out before recommending biologic therapy to ensure it is appropriate and forms part of a well-considered joint preservation plan.

Why Choose Dr. Raja Nadar for Joint Preservation?

Dr. Raja Nadar has fellowship training and clinical experience in orthopaedic surgery encompassing arthroscopy, trauma, and joint-related procedures. His approach to joint preservation integrates established surgical techniques with emerging biologic strategies to offer patients a comprehensive range of treatment options tailored to their individual needs and goals.